Human IL-21 R ELISA Kit/人IL-21 R ELISA试剂盒
货号：EH265RB,EH265RBX5,EH265RBX10
规格：96 tests,5X96 tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.61 ng/mL |
| 检测范围 | 0.61-150 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL21R |
| Protein aliases | CD360, IL-21 receptor, Interleukin-21 receptor, Novel interleukin receptor |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CD360, IL21R, NILR, UNQ3121/PRO10273 |
| Gene ID | (Human) 50615 |
| Gene symbol | IL21R |
| UniProt ID | (Human) Q9HBE5 |
| Human IL-21 R quantitates human IL-21 R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-21 R.人IL-21 R定量测定血清，血浆，上清液中的人IL-21R。该检测试剂盒将专门识别天然和重组人IL-21R。Target information 靶标信息The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.该基因编码的蛋白质是白介素21（IL21）的细胞因子受体。它属于I型细胞因子受体，已显示与共同的γ链形成异二聚体受体复合物，后者也是白介素2（IL2）和白介素5（IL5）的受体所共有的受体亚基。该受体转导IL21的生长促进信号，并且对于T细胞，B细胞和自然杀伤（NK）细胞的增殖和分化很重要。该受体的配体结合导致包括JAK1，JAK3，STAT1和STAT3在内的多个下游信号分子的激活。小鼠中类似基因的基因敲除研究表明，该基因在调节免疫球蛋白的产生中起作用。已经描述了编码相同蛋白质的三个选择性剪接的转录变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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