Human IL-23 R ELISA Kit/人IL-23 R ELISA试剂盒
货号:EH268RB,EH268RBX5,EH268RBX10
规格:96 tests,5X96 tests,10X96 tests
价格:6327,28472,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:人
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.2 ng/mL |
检测范围 | 0.2-50 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | IL23R |
Protein aliases | IL-23 receptor, Interleukin-23 receptor |
物种(Tested) | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | IL23R |
Gene ID | (Human) 149233 |
Gene symbol | IL23R |
UniProt ID | (Human) Q5VWK5 |
Human IL-23 R quantitates human IL-23 R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-23 R.人IL-23 R定量测定血清,血浆,上清液中的人IL-23R。 该检测试剂盒将专门识别天然和重组人IL-23R。Target information 靶标信息IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.IL-23R是一种629氨基酸的细胞因子IL23A / IL23受体新亚基,它与受体分子IL12RB1 / IL12R beta 1配对,因此参与IL23A信号传导。 信号转导分析证实该蛋白与Janus激酶2(JAK2)组成性缔合,并且还以配体依赖性方式与转录激活因子STAT3结合。 选择性剪接导致IL-23R的六个剪接同工型。 报告表明,IL-23R在牛皮癣发病机理中起着重要作用,也是炎症性肠病的潜在治疗靶标。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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