Human Coagulation Factor XI ELISA Kit/人凝血因子XI ELISA试剂盒
货号：EH118RB,EH118RBX5,EH118RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 10 pg/mL |
| 检测范围 | 10-2,500 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Factor XI |
| Protein aliases | Coagulation factor XI, Coagulation factor XIa heavy chain, Coagulation factor XIa light chain, FXI, Plasma thromboplastin antecedent, PTA |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | F11, FXI |
| Gene ID | (Human) 2160 |
| Gene symbol | F11 |
| UniProt ID | (Human) P03951 |
| Human Coagulation Factor XI quantitates human Coagulation Factor XI in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Coagulation Factor XI.人凝血因子XI定量测定血清，血浆，上清液中人凝血因子XI。 该检测试剂盒将专门识别天然和重组人凝血因子XI。Target information 靶标信息This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.该基因编码凝血级联的凝血因子XI。 该蛋白质以酶原的形式存在于血浆中，是一种独特的血浆凝结酶，因为它是同型二聚体，由两个通过二硫键连接的相同多肽链组成。 在激活血浆因子XI的过程中，内部肽键被两条链中的每条因子XIIa（或XII）裂解，产生了活化的因子XIa，这是一种丝氨酸蛋白酶，由两条重链和两条轻链通过二硫键连接 。 激活的血浆因子XI通过激活因子IX触发了凝血固有过程的中间阶段。 该因子的缺陷会导致Rosenthal综合征，这是血液凝固异常。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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