Human IL-27 R alpha ELISA Kit/人IL-27 R alpha ELISA试剂盒
货号:EH272RB,EH272RBX5,EH272RBX10
规格:96 Tests,5X96 Tests,10X96 tests
价格:6327,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:人
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.85 ng/mL |
检测范围 | 0.85-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | TCCR |
Protein aliases | class I cytokine receptor, Cytokine receptor WSX-1, Cytokine receptor-like 1, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, interleukin 27 receptor, alpha, Interleukin-27 receptor subunit alpha, T-cell cytokine receptor type 1, TCCR, Type I T-cell cytokine receptor, ZcytoR1 |
物种(Tested) | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | CRL1, IL-27RA, IL27R, IL27RA, TCCR, UNQ296/PRO336, WSX1, zcytor1 |
Gene ID | (Human) 9466 |
Gene symbol | IL27RA |
UniProt ID | (Human) Q6UWB1 |
Human IL-27 R alpha quantitates human IL-27 R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-27 R alpha.人IL-27 R alpha定量检测血清,血浆,上清液中的人IL-27 R alpha。 该检测试剂盒将只识别天然和重组人IL-27 Rα。Target information 靶标信息Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.抗原攻击后,T辅助细胞分化为两个功能不同的亚群Th1和Th2。 Th1细胞产生IL-2,IFN-γ和淋巴毒素β,从而增强细胞介导的免疫反应,而Th2细胞分泌能够增强体液免疫的IL-4,IL-5和IL-10。 T辅助细胞的功能受细胞因子调节。 最近鉴定并克隆了一种新的细胞因子受体。 它是I型细胞因子受体家族的新成员,并指定为T细胞细胞因子受体和WSX-1的TCCR。 TCCR缺陷的小鼠损害了Th1对蛋白质抗原攻击的反应,包括IFN-γ和Th1依赖性抗体IgG2a水平降低。 TCCR主要在胸腺,脾脏,淋巴液和外周血白细胞中表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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