PPP4C Polyclonal Antibody

货号：PA5-83682

规格：100 µL

价格：6049

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human PPP4C

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.2mg/mL	用法：	0.25-2 µg/mL(ICC) ;0.25-2 µg/mL(IF);1:2500-1:5000(IHC(P));0.04-0.4 µg/mL(WB)

产品详细信息Immunogen sequence: MAEISDLDRQ IEQLRRCELI KESEVKALCA KAREILVEES NVQRVDSPVT VCG靶标信息The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

数据：

PPP4C Antibody (PA5-83682) in IFImmunofluorescent analysis of PPP4C in U-2 OS cells using a PPP4C polyclonal antibody (Product # PA5-83682). The analysis shows localization to nucleus, plasma membrane and cytosol. PPP4C Antibody (PA5-83682) in IHCImmunohistochemical analysis of PPP4C in human testis using a PPP4C polyclonal antibody (Product # PA5-83682). The analysis shows high expression. PPP4C Antibody (PA5-83682) in WBWestern blot analysis of PPP4C by a PPP4C polyclonal antibody (Product # PA5-83682). Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 Lane 2: Human cell line RT-4.

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