Porcine IL-8 ELISA Kit/猪IL-8 ELISA试剂盒
货号：ES15RB,ES15RBX5
规格：96 Tests,5X96 Tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：其它
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 10 pg/mL |
| 检测范围 | 10-2,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL-8 |
| Protein aliases | Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, IL-8, Interleukin-8 |
物种（Tested） | 猪 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | AMCF-I, CXCL8, IL8 |
| Gene ID | (Pig) 396880 |
| Gene symbol | CXCL8 |
| Porcine IL-8 quantitates porcine IL-8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine IL-8.猪IL-8定量测定血清，血浆，上清液中的猪IL-8。该检测试剂盒将只识别天然和重组猪IL-8。Target information 靶标信息Interleukin 8 (IL-8, CXCL8) is a 72 amino acid pro-inflammatory factor which belongs to the CXC subfamily of chemokines, and are bound by the cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and potent angiogenic factor. The expression and secretion of IL-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is present in storage vesicles called Weibel-Palade bodies. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Previous nomenclature for IL-8 includes neutrophil activating protein 1 (NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C. IL-8 and ten other members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumours, and IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.白介素8（IL-8，CXCL8）是一种72个氨基酸的促炎因子，属于趋化因子的CXC亚家族，并与细胞表面受体IL-8RA和IL-8RB结合。 IL-8用作化学吸引剂和有效的血管生成因子。 IL-8的表达和分泌可通过多种细胞（包括巨噬细胞和内皮细胞）中的多种炎症刺激来诱导。在内皮细胞中，IL-8存在于称为Weibel-Palade体的储泡中。首先从骨肉瘤细胞中分离出来的IL-8含有ELR-基序（N端Glu-Leu-Arg氨基酸序列），并通过CXCR1和CXCR2受体发出信号。 IL-8的先前命名法包括嗜中性粒细胞激活蛋白1（NAP-1），粒细胞趋化蛋白1（GCP-1），单核细胞衍生的嗜中性粒细胞激活肽（MONAP）和蛋白3-10C。 IL-8和CXC趋化因子基因家族的其他十个成员在映射到染色体4q的区域中形成趋化因子基因簇。癌症研究表明IL-8在肿瘤的血管生成和生长中起作用，据信IL-8在毛细支气管炎（一种由病毒感染引起的常见呼吸道疾病）的发病机理中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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