PHF8 Polyclonal Antibody

货号：PA5-40090

规格：50 µg

价格：4880

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Three different KLH-conjugated synthetic peptides

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1.3 mg/mL	用法：	1:6,500(ELISA);1:1000(WB)

靶标信息PHD finger protein 8 is a jumonji domain containing protein. Like other members of the jumonji family, PHF8 may therefore play a role in histone demethylation. Mutations in PHF8 lead to Siderius type X-linked mental retardation (MRXSSD), a mild to borderline type of mental retardation.

数据：

PHF8 Antibody (PA5-40090) in WBE14TG2A mouse embryonic stem cells were transfected with a conditional allele of PHF8. Nuclear extracts (135 µg) from wild type cells (WT) and from 2 clones (F1, B8) with an active and a targeted allele (F1ko, B8ko), respectively, were analyzed by Western Blot using a PHF8 polyclonal antibody (Product # PA5-40090) at a dilution of 1:1,000. The position of the protein of interest is indicated on the right; the marker (kDa) is shown on the left. PHF8 Antibody (PA5-40090) in ELISATo determine the titer of the antibody, an ELISA was performed using a serial dilution of the anti-human PHF8 antibody (Product # PA5-40090), crude serum and Flow Through in antigen coated wells. By plotting the absorbance against the antibody dilution, the titer of the antibody was estimated to be 1:6,500

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