Mouse SLAM/CD150 ELISA Kit/小鼠SLAM / CD150 ELISA试剂盒
货号：EM70RB,EM70RBX5,EM70RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：小鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.06 ng/mL |
| 检测范围 | 0.06-12 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD150 |
| Protein aliases | CD150, signaling lymphocyte activation molecule, Signaling lymphocytic activation molecule, SLAM family member 1 |
物种（Tested） | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | 4933415F16, AA177906, CD150, CDw150, ESTM51, IPO-3, Slam, Slamf1 |
| Gene ID | (Mouse) 27218 |
| Gene symbol | Slamf1 |
| UniProt ID | (Mouse) Q9QUM4 |
| Mouse SLAM/CD150 quantitates mouse SLAM/CD150 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse SLAM/CD150.小鼠SLAM / CD150定量分析血清，血浆，上清液中的小鼠SLAM / CD150。该检测试剂盒将专门识别天然和重组小鼠SLAM / CD150。Target information 靶标信息CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).CD150（SLAM，信号淋巴细胞激活分子）属于免疫球蛋白基因超家族，参与T细胞刺激。 SLAM在外周血记忆T细胞，T细胞克隆，未成熟胸腺细胞和一定比例的B细胞上组成性表达，并在激活后迅速在幼稚T细胞上诱导。活化的B细胞表达SLAM的膜结合形式，可溶形式和细胞质同工型。提示在B到B和B到T细胞相互作用期间通过同源SLAM-SLAM结合的信号传导增强了活化的B细胞的扩增和分化。报告表明，CD150的胞外域是麻疹病毒的受体，并在T细胞和B细胞上起共激活剂的作用。此外，认为CD150通过其胞质结构域与SH2D1A和PTPN11相互作用。 CD150基因突变可能与X连锁淋巴增生性疾病（XLP）相关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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