Mouse Activin A ELISA Kit/小鼠激活素A ELISA试剂盒
货号：EM3RB,EM3RBX5,EM3RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：小鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.5 pg/mL |
| 检测范围 | 0.5-100 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | Activin A |
| Protein aliases | Activin beta-A chain, Inhibin beta A chain |
物种（Tested） | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | Inhba |
| Gene ID | (Mouse) 16323 |
| Gene symbol | Inhba |
| UniProt ID | (Mouse) Q04998 |
| Mouse Activin A quantitates mouse Activin A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Activin A.小鼠激活素A定量检测血清，血浆，上清液中的小鼠激活素A。该检测试剂盒将专门识别天然和重组小鼠激活素A。Target information 靶标信息Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.激活素是二聚体生长和分化因子，属于结构相关信号蛋白的转化生长因子-β（TGF-beta）超家族。激活素通过受体丝氨酸激酶的异聚复合物发出信号，所述受体丝氨酸激酶包括至少两种I型（I和IB）和两种II型（II和IIB）受体。这些受体都是跨膜蛋白，由具有半胱氨酸富集区的配体结合细胞外结构域，跨膜结构域和具有预测的丝氨酸/苏氨酸特异性的胞质结构域组成。 I型受体对于信号转导至关重要。 II型和II型受体对于结合配体和I型受体的表达是必需的。 I型和II型受体在配体结合后形成稳定的复合物，导致I型受体被II型受体磷酸化。激活素A突变与进行性骨化增生有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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