Mouse Semaphorin 4D/CD100 ELISA Kit/小鼠Semaphorin 4D / CD100 ELISA试剂盒
货号:EM68RB,EM68RBX5,EM68RBX10
规格:96 Tests,5X96 Tests,10X96 tests
价格:6641,29884,57271
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:小鼠
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 23 pg/mL |
检测范围 | 23-5,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | CD100 (SEMA4D) |
Protein aliases | CD100, M-Sema G, Sema J, semaphorin H, Semaphorin-4D, Semaphorin-C-like 2, Semaphorin-J |
物种(Tested) | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | CD100, coll-4, Sema4d, Semacl2, Semaj, Semcl2 |
Gene ID | (Mouse) 20354 |
Gene symbol | Sema4d |
UniProt ID | (Mouse) O09126 |
Mouse Semaphorin 4D/CD100 quantitates mouse Semaphorin 4D/CD100 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Semaphorin 4D/CD100.小鼠Semaphorin 4D / CD100定量检测血清,血浆,上清液中的小鼠Semaphorin 4D / CD100。 该检测试剂盒将专门识别天然和重组小鼠Semaphorin 4D / CD100。Target information 靶标信息Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.信号量是神经元化学趋化剂,可在神经系统发育过程中引导先驱神经元。 150 kDa的同型二聚体CD100(也称为信号量4d)是一种新型的信号量,可以诱导B细胞聚集并提高其在体外的生存能力。 CD100通过增加B细胞聚集和存活并下调CD23表达来修饰CD40-CD40L B细胞信号传导。 CD72是IV类信号量CD100的淋巴细胞受体,参与调节B细胞信号传导。 CD100在静止和PHA刺激的T细胞上表达。 该蛋白在NK细胞,EBV转化的B细胞,单核细胞和肿瘤/外周血T细胞系上表达较弱,而在活化T细胞和B细胞上则以较高的密度表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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