CD5 Monoclonal Antibody (UCHT2), PerCP-eFluor 710

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CD5 Monoclonal Antibody (UCHT2), PerCP-eFluor 710

货号:46-0059-42

规格:100 Tests

价格:3402

产品类型:流式抗体

品牌:eBioscience

抗原:CD5

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:UCHT2

荧光染料:PerCP-eFluor™ 710

类型:单抗同型对照:Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PerCP-eFluor 710
浓度: 5 µL/Test用法:5 µL (0.125 µg)/test(Flow)
产品详细信息Description: The UCHT2 monoclonal antibody reacts with human CD5, a 67 kDa protein expressed by a majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation.\\\\The monoclonal antibody UCHT2 recognizes primate CD5.Applications Reported: This UCHT2 antibody has been reported for use in flow cytometric analysis.靶标信息CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
数据

CD5 Antibody (46-0059-42) in FlowStaining of normal human peripheral blood cells with Anti-Human CD19 APC (Product # 17-0199-42) and Mouse IgG1 K Isotype Control PerCP-eFluor® 710 (Product # 46-4714-82) (left) or Anti-Human CD5 PerCP-eFluor® 710 (right). Cells in the lymphocyte gate were used for analysis.
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