CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), Biotin,

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CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), Biotin,

货号:13-0247-82

规格:100 µg

价格:1545

产品类型:流式抗体

品牌:eBioscience

抗原:CD24

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:eBioSN3 (SN3 A5-2H10

荧光染料:Biotin

类型:单抗同型对照:Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin
浓度: 0.5 mg/mL用法:0.25 µg/test(Flow)
产品详细信息Description: The SN3 monoclonal antibody reacts with the human CD24 molecule, also known as Heat Stable Antigen (HSA). This 35-50 kDa molecule is anchored in the plasma membrane via phosphatidylinositol and is expressed by erythrocytes, thymocytes, peripheral lymphocytes and myeloid lineage. It has been reported that P-selectin (CD62P) binds to CD24.Applications Reported: This eBioSN3 (SN3 A5-2H10) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioSN3 (SN3 A5-2H10) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, andcontrol of autoimmunity.
数据

CD24 Antibody (13-0247-82) in FlowStaining of normal human peripheral blood cells with 0.125 µg of Mouse IgG1 K Isotype Control Biotin (Product # 13-4714-85) (open histogram) or 0.125 µg of Anti-Human CD24 Biotin (filled histogram) followed by Streptavidin PE (Product # 12-4317-87). Cells in the large scatter population were used for analysis.
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参考文献
1. Journal of cell scienceEpigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state.2. TheranosticsGlutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling.3. Nature communicationsMrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.4. Nature communicationsMrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.5. Molecular cancerHOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells.

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