CD24 Monoclonal Antibody (eBioSN3 (SN3 A5-2H10)), PE-Cyanine7,
货号：25-0247-41,25-0247-42
规格：25 Tests,100 Tests
价格：1411,3478
产品类型：流式抗体
品牌：eBioscience
抗原：CD24
物种：人
宿主：小鼠
抗体亚型：IgG1, kappa
克隆号：eBioSN3 (SN3 A5-2H10
荧光染料：PE-Cy7
| 类型: | 单抗 | 同型对照： | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-Cyanine7 |
| 浓度： | 5 µL/Test | 用法： | 5 µL (0.5 µg)/test(Flow) |
产品详细信息Description: The eBioSN3 (SN3 A5-2H10) monoclonal antibody reacts with the human CD24 molecule, also known as Heat Stable Antigen (HAS). This 35-50 kDa molecule is anchored in the plasma membrane via phosphatidylinositol and is expressed by erythrocytes, thymocytes, peripheral lymphocytes and myeloid lineage. It has been reported that P-selectin (CD62P) binds to CD24.Applications Reported: This eBioSN3 (SN3 A5-2H10) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioSN3 (SN3 A5-2H10) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.Excitation: 488-561 nm; Emission: 775 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, andcontrol of autoimmunity.
| 数据 |
CD24 Antibody (25-0247-41) in FlowStaining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PE-Cyanine7 (Product # 25-4714-80) (blue histogram) or Anti-Human CD24 PE-Cyanine7 (purple histogram). Cells in the granulocyte gate were used for analysis. |
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| 参考文献 |
| 1. OncogeneTFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis.2. TheranosticsGlutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling.3. BMC biologyThe Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states.4. Breast cancer research : BCRThe hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.5. Molecular cancerHOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells. |
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