CD57 Monoclonal Antibody (TB01 (TBO1)), eFluor 450, eBioscience

货号：48-0577-42

规格：100 Tests

价格：2844

产品类型：流式抗体

品牌：eBioscience

抗原：CD57

物种：人

宿主：小鼠

抗体亚型：IgM

克隆号：TB01 (TBO1)

荧光染料：eFluor 450

抗体类型:	流式抗体	同型对照：	Mouse IgM Isotype Control (11E10), eFluor 450, eBioscience
浓度：	5 µL/Test	用法：	5 µL (0.5 µg)/test (Flow）

产品详细信息Description: This TB01 monoclonal antibody reacts with human CD57 (also known as HNK-1 and Leu-7), a 110-kDa cell surface glycoprotein expressed on a subset of natural killer (NK) cells and NK T cells.Applications Reported: This TB01 (TBO1) antibody has been reported for use in flow cytometric analysis.Applications Tested: This TB01 (TBO1) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.Filtration: 0.2 µm post-manufacturing filtered.靶标信息The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.仅用于科研。不用于诊断过程。未经明确授权不得转售。

数据

CD57 Antibody (48-0577-42) in FlowStaining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) APC (Product # 17-0567-42) and Mouse IgM Isotype Control eFluor® 450 (Product # 48-4752-80) (left) or Anti-Human CD57 eFluor® 450 (right). Cells in the lymphocyte gate were used for analysis.

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参考文献：

1.Cell reportsMass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells."Published figure using CD57 monoclonal antibody (Product # 48-0577-42) in Flow Cytometry"2.Nature communicationsUnique transcriptional and protein-expression signature in human lung tissue-resident NK cells."Published figure using CD57 monoclonal antibody (Product # 48-0577-42) in Flow Cytometry"3.Journal of immunology (Baltimore, Md. : 1950)IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production."48-0577 was used in Flow cytometry/Cell sorting to suggest that very low concentrations of IL-15 play an important role in boosting accessory cell function to support NK cell effector functions."

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