Rabbit anti Human RAE1 antibody
货号:VPA00805
规格:100 µl
价格:3171
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:RAE1
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Rabbit anti Human RAE1 antibodyrecognizes RAE1, also known as mRNA export factor, RAE1 RNA export 1 homolog, homolog of yeast Rae1 mRNA-associated protein of 41 kDa, mRNA export protein, or mRNA-associated protein MRNP 41.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. RAE1 is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for RAE1 (provided by RefSeq, Jul 2008).Rabbit anti Human RAE1 antibody detects a band of 41 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography on immunogen. |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3)2% Sucrose |
Immunogen | Synthetic peptide directed towards the C terminal region of human RAE1 |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 多克隆抗体
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