Rabbit anti Human glutathione peroxidase 1 antibody
货号:VPA00488
规格:100 µl
价格:2890
产品类型:免疫组化一抗
品牌:Bio-Rad
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Rabbit anti Human glutathione peroxidase 1 antibodyrecognizes glutathione peroxidase 1, also known as GPx-1, GSHPx-1 or cellular glutathione peroxidase.GPX1 gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for GPX1 (provided by RefSeq, Jul 2008).Rabbit anti Human glutathione peroxidase 1 antibody detects a band of 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
Buffer Solution | Phosphate buffered saline. |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
Immunogen | KLH conjugated synthetic peptide corresponding to amino acid 164-193 of human glutathione peroxidase 1 |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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