产品介绍 | | |
Rabbit anti Human HLA-DQA2 antibodyrecognizes the HLA class II histocompatibility antigen DQ alpha 2 chain, also known as DX alpha chain, HLA class II histocompatibility antigen, DQ (6) alpha chain or MHC class II DQA2.HLA-DQA2 belongs to the HLA class II alpha chain family. The HLA-DQA2 gene encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B-cells, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells (provided by RefSeq, Jun 2010).Rabbit anti Human HLA-DQA2 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
Buffer Solution | Phosphate buffered saline. |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
Immunogen | KLH conjugated synthetic peptide corresponding to amino acid 39-66 of human HLA-DQA2 |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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