Rabbit anti Human catenin beta antibody
货号：VPA00164
规格：100 µl
价格：3171
产品类型：免疫组化一抗
品牌：Bio-Rad
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human catenin beta antibodyrecognizes the catenin beta, also known as beta-catenin.Catenin beta is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Catenin beta binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in catenin beta are a cause of colorectal cancer, pilomatrixoma (PTR), medulloblastoma (MDB) and ovarian cancer. Three transcript variants encoding the same protein have been found for catenin beta (provided by RefSeq, Oct 2009).Rabbit anti Human catenin beta antibody detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline. |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3) |
| Immunogen | Synthetic peptide corresponding to the C terminus of catenin beta |
| Approx. Protein Concentrations | IgG concentration 1.15 mg/ml |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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