Mouse anti Human filamin-A antibody
货号：VMA00322
规格：100μl
价格：2916
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：filamin-A
物种：人
宿主：小鼠
抗体亚型：IgG1
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human filamin-A antibodyrecognizes filamin-A, also known as actin binding protein 280, alpha-filamin, endothelial actin-binding protein, filamin-1 and non-muscle filamin.Filamin-A, encoded by FLNA gene, is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. This protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. Filamin-A interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in the FLNA gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for FLNA (provided by RefSeq, Mar 2009).Mouse anti Human filamin-A antibody detects a band of 280 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
| Immunogen | Purified His-tagged filamin-A |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch. |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | 1/1000 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood. |
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技术参数 产品应用 wb
产品类型 单克隆抗体
推荐用于 wb
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