Mouse anti Human PIN1 antibody
货号：VMA00303
规格：100μl
价格：2916
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：PIN1
物种：人
宿主：小鼠
抗体亚型：IgG1
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human PIN1 antibodyrecognizes the peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, also known as PPIase Pin1, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 and rotamase Pin1.Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Encoded by the PIN1 gene, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for PIN1 (provided by RefSeq, Jun 2011).Mouse anti Human PIN1 antibody detects a band of 18 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Mouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
| Immunogen | Purified His-tagged PIN1 protein |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch. |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | 1/1000 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood. |
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技术参数 产品应用 wb
产品类型 单克隆抗体
推荐用于 wb
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