Mouse anti human CD47 antibody, clone BRIC126
货号：MCA911T,MCA911
规格：25 µg,0.2 mg
价格：893,3783
产品类型：流式抗体
品牌：Bio-Rad
抗原：CD47
物种：人
宿主：小鼠
抗体亚型：IgG2b
克隆号：BRIC126
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti human CD47 antibody, clone BRIC126recognises the human CD47 cell surface glycoprotein, a heavily N-glycosylated 47-52 kDa molecule. CD47 is expressed on all cells and tissues so far examined, although expression is reduced on erythrocytes of the rare Rh null phenotype. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Buffer Solution | TRIS buffered glycine |
| Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
| Approx. Protein Concentrations | Pack Size: 0.2 mgIgG concentration 1 mg/mlPack Size: 25 µgIgG concentration 1.0 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.Avent, N.et al.(1988) Monoclonal antibodies that recognize different membrane proteins that are deficient in Rhnull human erythrocytes. One group of antibodies reacts with a variety of cells and tissues whereas the other group is erythroid-specific.Biochem J. 251 (2): 499-505.2.Ide, K.et al.(2007) Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.Proc Natl Acad Sci U S A. 104 (12): 5062-6.3.Lecchi, C.et al.(2008) Bovine alpha-1 acid glycoprotein can reduce the chemotaxis of bovine monocytes and modulate CD18 expression.Vet Res. 39: 50.4.Chao, M.P.et al.(2011) Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.Cancer Res. 71 (4): 1374-84. |
技术参数 产品应用 Flow;WB
产品类型 Monoclonal Antibody
推荐用于 Flow;WB
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