Mouse anti Human CD94 antibody, clone DX22
货号：MCA2254
规格：0.2 mg
价格：3400
产品类型：流式抗体
品牌：Bio-Rad
抗原：CD94
物种：人
宿主：小鼠
抗体亚型：IgG1
克隆号：DX22
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human CD94 antibody, clone DX22recognizes human Natural killer cells antigen CD94, also known as KLRD1, Killer cell lectin-like receptor, subfamily D, member 1, CD94, KP43 and NK cell receptor. CD94 is a 179 amino acid single pass type II transmembrane glycoprotein with a predicted molecular mass of ~20.5 kDa. There are 3 isoforms of CD94 derived by alternative splicing.CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes.CD94 is found to associate with NKG2 to form a heterodimer, involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.Mouse anti Human CD94 antibody, clone DX22 is reported to inhibit the binding of CD94 to HLA-E (Braudet al.1998) and HLA-G (Söderström.et al.1997). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Immunogen | Natural killer cell line. |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Preservative Stabilisers | 0.09%Sodium Azide |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) | STAR117A | F | 0.5mg |
| 文献 |
| 1.Phillips, J.H.et al.(1996) CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.Immunity. 5 (2): 163-72.2.Braud, V.M.et al.(1998) HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.Nature. 391 (6669): 795-9.3.Tomasec, P.et al.(2000) Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Science. 287 (5455): 1031. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
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