| 产品介绍 | | |
| Mouse anti Rat CD61 antibody, clone F11recognizes the rat CD61 cell surface antigen, also known as the integrin b3 chain.CD61 is expressed by platelets, megakaryocytes and osteoclasts.Clone F11 has been shown to inhibit thein vitroattachment of osteoclasts to various proteins including vitronectin, fibrinogen and von Willebrand Factor (Sicket al.2009). |
| 产品详情 | | |
| Target Species | Rat |
| Product Form | Purified IgG - liquid |
| Species Cross-Reactivity | Target Species | Cross Reactivity |
| Human | Weak |
| N.B. Antibody reactivity and working conditions may vary between species. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09%Sodium Azide |
| Carrier Free | Yes |
| Immunogen | Human myeloperoxidase |
| Fusion Partners | Spleen cells from immunized mice were fused with cells of the mouse X63 AG8-653 myeloma cell line |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Flow Cytometry | √ | 1/50 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 推荐产品 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed) | STAR117A | F | 0.5mg |
| 文献 |
| 1.Helfrich, M.H.et al.(1992) Integrins on rat osteoclasts: characterization of two monoclonal antibodies (F4 and F11) to rat beta 3.J Bone Miner Res. 7 (3): 345-51.2.Shankar, G.et al.(1993) Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts.J Cell Sci. 105 ( Pt 1): 61-8.3.Sick, E.et al.(2009) Activation of CD47 receptors causes histamine secretion from mast cells.Cell Mol Life Sci. 66: 1271-82.4.Wang, Z.et al.(2015) Microparticle levels after arterial injury andNOtherapy in diabetes.J Surg Res. pii: S0022-4804(15)00867-7 |
QQ:1749072012