Rabbit anti Human beta amyloid antibody
货号:AHP677
规格:0.1 ml
价格:4063
产品类型:免疫组化一抗
品牌:Bio-Rad
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:其它
产品介绍 | | |
Rabbit anti Human beta amyloid antibodyrecognizes the beta amyloid (1-42) peptide, the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease (Benvenisteet al.2015). Beta amyloid also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy (Kirshneret al.2015).Rabbit anti Human beta amyloid antibody (AHP677) may be used in immunohistochemical staining of Alzheimer's disease plaques. |
产品详情 | | |
Target Species | Human |
Product Form | Serum - liquid |
Antiserum Preparation | Antisera to Beta amyloid (1-42) were raised by repeated immunisations of rabbits with highly purified antigen. |
Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining alquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
ELISA | √ | | |
Immunohistology - Frozen | √ | | |
Western Blotting | √ | 1/500 | 1/1000 |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
二抗 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E,WB | 1mg |
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C,E,WB | 1mg |
文献 |
1.Bertrand, E.et al(2008) Amyloid angiopathy in idiopathic Parkinson's disease. Immunohistochemical and ultrastructural study.Folia Neuropathologica. 46: 255-269.2.Carty, N.C.et al.(2006) Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice.J Neuroinflammation. 3: 11.3.Jeffrey, M.et al.(2015) Membrane pathology and microglial activation of mice expressing membrane anchored or membrane released forms of Aβ and mutated human Alzheimer's precursor protein (APP).Neuropathol Appl Neurobiol. 41 (4): 458-70.4.Jeffrey Met al.(2015) A Naturally Occurring Bovine Tauopathy Is Geographically Widespread in the UK.PLoS One. 10 (6): e0129499. |
技术参数 产品应用 wb
产品类型 Polyclonal Antibody
推荐用于 wb
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