Rabbit anti P90RSK1 antibody
货号：AHP2710
规格：50 µl
价格：3188
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：P90RSK1
物种：其它
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti P90RSK1 antibodyrecognizes recognizes ribosomal protein S6 kinase alpha-1, also known as p90S6K, MAPK-activated protein kinase 1a, MAPKAPK-1a and RSK-1. It belongs to the RSK (ribosomal S6 kinase) family of serine/threonine kinases (Fisher and Blenis 1996). It is a downstream effector of Ras/ERK signalling pathway (Casalvieri et al. 2017). It directly phosphorylates IkappaBbeta and activates NF-kappaB (Xu et al. 2006). It has been reported to phosphorylate CREB on Ser133 (Cho et al. 2011). RSK also promotes mTOR signaling and translation (Shahbazian et al. 2006). Expression and activity of RSK1 promotes tumor growth and survival (Casalvieri et al. 2017). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Antiserum Preparation | Antiserum to P90RSK1 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.02% Sodium Azide50% Glycerol |
| Immunogen | A synthetic peptide corresponding to a sequence from amino acid 600 to the C-terminus of human P90RSK1 |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | 1/500 | 1/1000 |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C,E,WB | 1mg |
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E,WB | 1mg |
技术参数 产品应用 wb
产品类型 Polyclonal Antibody
推荐用于 wb
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