Goat anti Androgen Receptor
货号：VPA00046
规格：100 µl
价格：3613
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：Androgen Receptor
物种：人
宿主：山羊
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Goat anti Human androgen receptor antibodyrecognizes the human androgen receptor (AR), also known as the dihydrotestosterone receptor or nuclear receptor subfamily 3 group C member 4. AR is a ligand-activated transcription factor that belongs to a large family of nuclear receptor proteins. Unbound AR resides predominately in the cytoplasm as a heteromeric complex with hsp90 and other chaperone proteins. These chaperone proteins maintain AR in a form that is receptive to ligand binding. Upon ligand binding, AR recruits a variety of factors including coactivators and mediator proteins whose enzymatic activities promote chromatin remodeling and transcriptional regulation of target genes leading to cell differentiation, survival, and proliferation.Mutated AR is strongly implicated in development of prostate adenocarcinoma and metastases development.Goat anti Human androgen receptor antibody recognizes androgen receptor as a single band of approximately 110 kDa in LNCaP cell lysates by western blotting under reducing conditions. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Goat polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | TRIS buffered saline. |
| Preservative Stabilisers | 0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin |
| Immunogen | Peptide with sequence EVQLGLGRVYPRPPSC from the N-terminus of the androgen receptor. |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
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