Sheep anti Human ceruloplasmin antibody
货号：1940-0004P
规格：1 ml
价格：3213
产品类型：免疫组化一抗
品牌：Bio-Rad
物种：人
宿主：Sheep
抗体亚型：IgG
荧光染料：HRP
| 产品介绍 | | |
| Sheep anti Human ceruloplasmin antibodydetects ceruloplasmin, a ~132kDa metalloprotein that is secreted into the plasma by liver hepatocytes and activated monocytes/macrophages. Ceruloplasmin functions in copper transport, iron homeostasis, antioxidant defence, angiogenesis and coagulation.Deficiency in ceruloplasmin is termed aceruloplasminemia, an autosomal recessive disorder which leads to iron accumulation and tissue damage, in particular in the brain and visceral organs. Clinical features include retinal degeneration, diabetes mellitus and neurological disturbances.Elevated plasma ceruloplasmin has been shown to pose an increased risk in atherosclerosis and myocardial infarction. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography |
| Buffer Solution | Phosphate buffered saline |
| Immunoge | Highly pure human ceruloplasmin. |
| Approx. Protein Concentrations | IgG concentration 5.0 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | 0.5 µg/ml | 1 µg/ml |
| Immunohistology - Frozen | √ | 10 µg/ml | 20 µg/ml |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Donkey anti Sheep/Goat IgG:DyLight®488 | STAR88D488GA | F,IF | 0.1mg |
| Rabbit anti Sheep IgG (H/L):Biotin | 5184-2304 | E,WB | 1.5 ml |
| 文献 |
| 1De Paula, M.L.et al.(2014) The PTEN inhibitor bisperoxovanadium enhances myelination by amplifying IGF-1 signaling in rat and human oligodendrocyte progenitors.Glia. 62 (1): 64-77.2。Preisner, A.et al.(2015) Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination.Acta Neuropathol. 130 (2): 247-61.3.Kuroda, M.et al.(2017) Peripherally derived FGF21 promotes remyelination in the central nervous system.J Clin Invest. 127 (9): 3496-509. |
技术参数 产品应用 Elisa
产品类型 Polyclonal Antibody
推荐用于 Elisa
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