产品介绍 | | |
| Mouse anti Human Osteocalcin antibody, clone 6F9G4E10recognizes intact human osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin.Osteocalcin (Bone Gla Protein) is a 49 amino acid ~5.8 kDa single chain vitamin K dependent protein, made by osteoblasts and major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency. |
产品详情 | | |
Target Species | Human |
Species Cross-Reactivity | Target Species | Cross Reactivity | |
| Bovine | × | |
| Mouse | × | |
| Rat | × | |
| N.B. Antibody reactivity and working conditions may vary between species. |
Product Form | Purified IgG - liquid |
Preparation | Purified IgG prepared by affinity chromatography on Protein A |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.09%Sodium Azide (NaN3) |
Carrier Free | Yes |
Immunogen | Recombinant human osteocalcin GST fusion protein. |
Approx. Protein Concentrations | 1.0 mg/ml |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
ELISA | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls. |
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Goat anti Mouse IgG (H/L):DyLight®680 (Multi Species Adsorbed) | STAR117D680GA | F WB | 0.1 mg |
Goat anti Mouse IgG (H/L):DyLight®800 (Multi Species Adsorbed) | STAR117D800GA | F IFWB | 0.1 mg |
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed) | STAR117F | F | 0.5 mg |
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) | STAR117P | C E WB | 0.5 mg |
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Goat anti Mouse IgG (Fc):HRP | STAR120P | E WB | 1 mg |
文献 |
| 1.Gindraux, F.<emet al.<="" em="" style="box-sizing: border-box;">(2010) Industrial approach in developing an advanced therapy product for bone repair.J Tissue Eng Regen Med. 4: 194-204.2.Hellman, J.et al.(2004) Isolated osteocalcin fragmentsUS Patent Application: US20040259167A1 |
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