CD79a Monoclonal Antibody (SP18)

货号：MA5-14556

规格：500 µL

价格：5548

产品类型：流式抗体

品牌：Thermo Fisher

物种：人/小鼠

宿主：兔

抗体亚型：IgG

克隆号：SP18

荧光染料：其它

类型:	单抗	同型对照：
浓度：		用法：	1:1,000-1:10,000 (WB)；1:100(IHC (P))；1:2 (Flow)

产品详细信息MA5-14556 targets CD79a in IHC (P), WB and FACS applications and shows reactivity with Human and Mouse samples.The MA5-14556 immunogen is synthetic peptide derived from N-terminal region of human CD79a protein.靶标信息CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

数据

CD79a Antibody (MA5-14556) in IHCFormalin-fixed, paraffin-embedded human tonsil stained with CD79a using peroxidase-conjugate and AEC. Note cell membrane staining of B cells

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参考文献：

1.Arthritis research & therapyUpregulation of tumor necrosis factor receptor-associated factor 6 correlated with synovitis severity in rheumatoid arthritis."MA5-14556 was used in Immunohistochemistry to investigate tumour necrosis factor receptor-associated factor 6 expression in the rheumatoid arthritis synovium, and its correlation with histological synovitis severity and radiological joint destruction in rheumatoid arthritis."2.Diagnostic pathologyComposite lymphoma in the anterior mediastinum: a case report and review of the literature."MA5-14556 was used in immunohistochemistry to present a case report of an unusual composite lymphoma in the mediastinum"3.HaematologicaIdentification of rare Epstein-Barr virus infected memory B cells and plasma cells in non-monomorphic post-transplant lymphoproliferative disorders and the signature of viral signaling."MA5-14556 was used in immunohistochemistry to investigate the role of Epstein-Barr virus infection in the immune response of non-monomorphic post-transplant lymphoproliferative disorders"4.Diagnostic cytopathologyLiquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology."MA5-14556 was used in immunocytochemistry to report on a case of solitary extramedullary plasmacytoma of the thyroid"

技术参数

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