货号：39-2400

规格：100 µg

价格：4809

产品类型：免疫组化一抗

品牌：Thermo Fisher

物种：人/小鼠

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号： 5H5L9

荧光染料：其它

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.