名称

货号

规格

价格

BAY-11-7082

1956772

10mg

1190

BAY-11-7082

1956772

25mg

2730

Applications

FA

Synonyms:

(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile

Formulation:

Crystalline solid

Chemical Name:

(E)-3-(4-methylphenyl)sulfonylprop-2-enenitrile

Molecular Formula:

C₁₀H₉NO₂S

Molecular Weight:

207.3

CAS Number

19542-67-7

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Mori, N., Yamada, Y., Ikeda, S., Yamasaki, Y., Tsukasaki, K., Tanaka, Y., ... & Fujii, M. (2002). Bay 11-7082 inhibits transcription factor NF-κB and induces apoptosis of HTLV-I–infected T-cell lines and primary adult T-cell leukemia cells.Blood,100(5), 1828-1834.

Lappas, M., Yee, K., Permezel, M., & Rice, G. E. (2005). Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-κB and IκB kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro.Endocrinology,146(3), 1491-1497.

García, M. G., Alaniz, L., Lopes, E. C., Blanco, G., Hajos, S. E., & Alvarez, E. (2005). Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines.Leukemia research,29(12), 1425-1434.