Applications

FA

Synonyms:

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, LY-294002

Formulation:

Crystalline solid

Chemical Name:

2-morpholin-4-yl-8-phenylchromen-4-one

Molecular Formula:

C₁₉H₁₇NO₃

Molecular Weight:

307.3

CAS Number

154447-36-6

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Gharbi, S., Zvelebil, M., Shuttleworth, S., Hancox, T., Saghir, N., Timms, J., & Waterfield, M. (2007). Exploring the specificity of the PI3K family inhibitor LY294002.Biochem. J,404, 15-21.

Vlahos, C. J., Matter, W. F., Hui, K. Y., & Brown, R. F. (1994). A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).Journal of Biological Chemistry,269(7), 5241-5248.

Sanchezmargalet, V., Goldfine, I. D., Vlahos, C. J., & Sung, C. K. (1994). Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002.Biochemical and biophysical research communications,204(2), 446-452