Applications

FA

Synonyms:

DM-3189

Formulation:

Crystalline solid

Chemical Name:

4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinolone

Molecular Formula:

C₂₅H₂₂N₆

Molecular Weight:

406.5

CAS Number

1062368-24-4

Purity:

≥95%

Storage Conditions:

Product should be kept at-20°C.

References:

Boergermann, J. H., Kopf, J., Yu, P. B., & Knaus, P. (2010). Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells. The international journal of biochemistry & cell biology, 42(11), 1802-1807

Kreitzer, F. R., Salomonis, N., Sheehan, A., Huang, M., Park, J. S., Spindler, M. J., ... & Conklin, B. R. (2013). A robust method to derive functional neural crest cells from human pluripotent stem cells. American journal of stem cells,2(2), 119.

Derwall, M., Malhotra, R., Lai, C. S., Beppu, Y., Aikawa, E., Seehra, J. S., ... & Paul, B. Y. (2012). Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, 32(3), 613-622.