Applications

FA

Synonyms:

UNII-PB12M2F8KY, Shh Signaling Antagonist VI

Formulation:

Crystalline solid

Chemical Name:

9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine

Molecular Formula:

C₃₁H₃₂N₆O₂

Molecular Weight:

520.6

CAS Number

483367-10-8

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Wu, X., Walker, J., Zhang, J., Ding, S., & Schultz, P. G. (2004). Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway.Chemistry & biology,11(9), 1229-1238.

Beloti, M. M., Bellesini, L. S., & Rosa, A. L. (2005). Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells.Cell biology international,29(7), 537-541.

Oliveira, F. S., Bellesini, L. S., Defino, H. L. A., da Silva Herrero, C. F., Beloti, M. M., & Rosa, A. L. (2012). Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells.Journal of cellular biochemistry,113(1), 204-208.