Prostaglandin E2

2024-10-15

Prostaglandin E2

货号:3632464-10,3632464-50

规格:10mg,50mg

价格:1155,5225

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :3632464

Description

Prostaglandin E2 is the most biologically active prostaglandin and exists in some level in nearly all cell types. It binds to EP1, EP2, Ep3, and Ep4 receptors and is involved in smooth muscle relaxation, inflammation, fertility, sleep cycle regulation, and gastric mucosal integrity.

Additional Information

Applications

FA

Synonyms:

Dinoprostone, PGE2, 13E-dien-1-oic acid

Formulation:

Crystalline solid

Chemical Name:

(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid

Molecular Formula:

C20H32O5

Molecular Weight:

352.5

CAS Number

363-24-6

Purity:

≥98%

Storage Conditions:

Product should be kept at-20°C.

References:

Sheng, H., Shao, J., Morrow, J. D., Beauchamp, R. D., & DuBois, R. N. (1998). Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells.Cancer Research,58(2), 362-366.

Betz, M., & Fox, B. S. (1991). Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines.The Journal of Immunology,146(1), 108-113.

Kunkel, S. L., Spengler, M., May, M. A., Spengler, R., Larrick, J., & Remick, D. (1988). Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.Journal of Biological Chemistry,263(11), 5380-5384.

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