Applications

FA

Synonyms:

2-(4-Morpholinoanilino)-6-cyclohexylaminopurine, CHEMBL188343

Formulation:

Crystalline solid

Chemical Name:

6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

Molecular Formula:

C₂₁H₂₇N₇O

Molecular Weight:

393.5

CAS Number

656820-32-5

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Chen, S., Takanashi, S., Zhang, Q., Xiong, W., Zhu, S., Peters, E. C., ... & Schultz, P. G. (2007). Reversine increases the plasticity of lineage-committed mammalian cells.Proceedings of the National Academy of Sciences,104(25), 10482-10487.

D'Alise, A. M., Amabile, G., Iovino, M., Di Giorgio, F. P., Bartiromo, M., Sessa, F., ... & Cortese, R. (2008). Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.Molecular cancer therapeutics,7(5), 1140-1149.

Anastasia, L., Sampaolesi, M., Papini, N., Oleari, D., Lamorte, G., Tringali, C., ... & Venerando, B. (2006). Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.Cell Death & Differentiation,13(12), 2042-2051.