Sodium Butyrate

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Sodium Butyrate

货号:1565474-50,1565474-250

规格:50g,250g

价格:275,1045

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :1565474

Description

Sodium Butyrate is the sodium salt of butyric acid that has the biological effect of inducing histone hyperacetylation and the inhibition of histone deacetylase (HDAC) activity. It is reported to induce apoptosis in a variety of cell lines and induce pancreatic progenitor formation. In combination with Activin A, sodium butyrate promotes the differentiation of hepatocytes from embryonic stem cells.

Additional Information

Applications

FA

Synonyms:

Butyric Acid, Sodium butanoate

Formulation:

Crystalline solid

Chemical Name:

Butanoic acid

Molecular Formula:

C4H7O2Na

Molecular Weight:

110.1

CAS Number

156-54-7

Purity:

≥95%

Storage Conditions:

Product should be kept at room temperature.

References:

Candido, E. P. M., Reeves, R., & Davie, J. R. (1978). Sodium butyrate inhibits histone deacetylation in cultured cells.Cell,14(1), 105-113.

Hague, A., Manning, A. M., Hanlon, K. A., Hart, D., Paraskeva, C., & Huschtscha, L. I. (1993). Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: implications for the possible role of dietary fibre in the prevention of large‐bowel cancer.International Journal of Cancer,55(3), 498-505.

Rambhatla, L., Chiu, C. P., Kundu, P., Peng, Y., & Carpenter, M. K. (2003). Generation of hepatocyte-like cells from human embryonic stem cells.Cell transplantation,12(1), 1-11.

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