Applications

FA

Synonyms:

T-0901317, T0901317

Formulation:

Crystalline solid

Chemical Name:

N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide

Molecular Formula:

C₁₇H₁₂F₉NO₃S

Molecular Weight:

481.3

CAS Number

293754-55-9

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Koldamova, R. P., Lefterov, I. M., Staufenbiel, M., Wolfe, D., Huang, S., Glorioso, J. C., ... & Lazo, J. S. (2005). The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease.Journal of Biological Chemistry,280(6), 4079-4088.

Mitro, N., Vargas, L., Romeo, R., Koder, A., & Saez, E. (2007). T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR.FEBS letters,581(9), 1721-1726.

Chisholm, J. W., Hong, J., Mills, S. A., & Lawn, R. M. (2003). The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse.Journal of lipid research,44(11), 2039-2048.