Recombinant Human IL-22
货号：200-22-10,200-22-100,200-22-1000,200-22-2,200-22-250,200-22-50,200-22-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,11069,44326,582,19355,6634,28757
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：IL-22 is a member of the IL-10 family of regulatory cytokines, which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10Rβ/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant Human IL-22 is a 33.6 kDa, non-disulfide-linked, homodimeric protein consisting of two 147 amino acid polypeptide chains.来源:E.coli别名:Interleukin-22, IL-TIF, Cytokine ZCYTO18氨基酸序列 (monomer):MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Assay #1:Determined by its ability to activate STAT following receptor ligand interaction.Assay #2:Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The expectedED50for this effect is 0.7- 1.0 ng/ml.Calculated Molecular Weight:33.6 kDaAccession Number:Q9GZX6Gene ID:50616交叉反应:Human,Monkey,Mous原产地:USA仅用于科研，不能用于临床和诊断。 |
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