Animal-Free Recombinant Human IL-13
货号：AF-200-13-2,AF-200-13-10,AF-200-13-50,AF-200-13-100,AF-200-13-250,AF-200-13-500,AF-200-13-1000
规格：2ug,10ug,50ug,100ug,250ug,500ug,1mg
价格：1250,2830,13160,21940,38400,57050,87780
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-200-13产品描述：IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:NC30 (Human), P600 (Murine)AA Sequence:MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFNPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to stimulate the proliferation of human TF-1 cells. The expectedED50is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥1 x 106units/mg.Calculated Molecular Weight:12.6 kDaAccession Number:P35225Gene ID:3596crossreactivity:Human,MouseCountry Of Origin:USANot for human use. |
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