Murine IGF-I
货号：250-19-10,250-19-100,250-19-1000,250-19-250,250-19-50,250-19-500
规格：10ug,100ug,1mg,250ug,50ug,500ug
价格：640,3280,13124,5733,1560,8518
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissuein vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant Murine IGF-I is a 7.6 kDa globular protein containing amino acids including 3 intra-molecular disulfide bonds.来源:E.coli别名:Insulin-like Growth Factor-I, Somatamedin C, IGF-IA氨基酸序列:GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50was determined a cell proliferation assay using FDC-P1 cells is≤2.0 ng/ml, corresponding to a specific activity of≥5 x 105units/mg.Calculated Molecular Weight:7.6 kDaAccession Number:P05017Gene ID:16000交叉反应: Human,Mouse,Pig,Rat |
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