Animal-Free Recombinant Human IL-4
货号：AF-200-04-5,AF-200-04-20,AF-200-04-50,AF-200-04-100,AF-200-04-250,AF-200-04-500,AF-200-04-1000
规格：5ug,20ug,50ug,100ug,250ug,500ug,100ug
价格：1250,2830,6460,10780,18860,32340,53900
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-200-04产品描述：IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant Human IL-4 is a 15.1 kDa globular protein containing 130 amino acid residues.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:BCGF, BCDF, B cell stimulating factor (BSF-1)AA Sequence:MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSSPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:TheED50was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106units/mg.Calculated Molecular Weight:15.1 kDaAccession Number:P05112Gene ID:3565crossreactivity:Human,MouseCountry Of Origin:USANot for human use. |
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