Animal-Free Recombinant Human PDGF-AA
货号：AF-100-13A-10,AF-100-13A-500,AF-100-13A-250,AF-100-13A-100,AF-100-13A-1000,AF-100-13A-50,AF-100-13A-2
规格：10ug,500ug,250ug,100ug,1mg,50ug,2ug
价格：1778,26157,17606,10437,40319,6257,791
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).Manufactured using all Animal-Free reagents.来源:E.coli别名:Platelet-Derived Growth Factor-AA, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)氨基酸序列:SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.Calculated Molecular Weight:28.5 kDa生物活性:Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expectedED50for this effect is 1.0-3.0 ng/ml.Accession Number:P04085Gene ID:5154交叉反应：Dog,Human,Monkey,Mouse,Rat,Salamander |
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