Animal-Free Recombinant Human PDGF-BB
货号：AF-100-14B-10,AF-100-14B-100,AF-100-14B-1000,AF-100-14B-50,AF-100-14B-250,AF-100-14B-2,AF-100-14B-500
规格：10ug,100ug,1mg,50 ug,250 ug,2ug,500ug
价格：1778,10437,40319,6257,17606,791,26157
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of twoβ chains (218 total amino acids). .Manufactured using all Animal-Free reagents.来源:E.coli别名:Platelet-Derived Growth Factor-BB, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)氨基酸序列:SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expectedED50for this effect is 1.0-3.0 ng/ml.Calculated Molecular Weight:24.3 kDaAccession Number:P01127Gene ID:5155交叉反应：Cow,Human,Monkey,Mouse,Pig,Rat |
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