Recombinant Human 4-1BB Ligand
货号：310-11-100,310-11-1000,310-11-20,310-11-250,310-11-5,310-11-500
规格：100ug,1mg,20ug,250ug,5ug,500ug
价格：6410,25699,1425,11216,585,16669
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane protein domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant Human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.来源:E.coliSynonyms:TNFSF9, CD137L氨基酸序列:MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by the dose-dependent stimulation of IL-8 production by human PBMC. TheED50for this effect is 5-10 ng/ml.Please Note: Results may vary with PBMC donors.Calculated Molecular Weight:19.5 kDaAccession Number:P41273Gene ID:8744交叉反应：Human,Mouse原产国:USA |
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