Recombinant Human APRIL
货号：310-10C-10,310-10C-100,310-10C-1000,310-10C-2,310-10C-250,310-10C-50,310-10C-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,11069,44326,582,19355,6634,28757
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of the colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, competes for two receptors, TACI and BCMA. APRIL has the ability to stimulate proliferation of various tumor cell lines, including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF-like receptor binding of the APRIL precursor. Recombinant Human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.*Human APRIL(Catalog Number 310-10C) has replaced Human APRIL(Catalog Number 310-10)来源:Hi-5 Insect cells别名:A Proliferation-Inducing Ligand, TNFSF13, TRDL-1, TALL-2, CD256氨基酸序列:AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to induce NF-κB activation in HEK293-NF-κB reporter cells transfected with BCMA receptor.Calculated Molecular Weight:16.3 kDaAccession Number:O75888Gene ID:8741交叉反应：Human,Mouse原产国:USA |
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