Recombinant Human BD-4
货号：300-65-100,300-65-1000,300-65-20,300-65-250,300-65-5,300-65-500
规格：100ug,1mg,20ug,250ug,5ug,500ug
价格：6410,25699,1425,11216,585,16669
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. BD-4 is expressed in the testes, stomach, uterus, neutrophils, thyroid, lungs and kidneys. In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes. Recombinant Human BD-4 is a 6.0 kDa protein containing 50 amino acid residues.别名:Beta-Defensin 104, DEFB4氨基酸序列:EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/ml.Calculated Molecular Weight:6 kDaAccession Number:Q8WTQ1Gene ID:140596原产地:USA仅用于科研，不能用于临床和诊断。 |
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