Recombinant Murine M-CSF
货号:315-02-10,315-02-100,315-02-1000,315-02-2,315-02-250,315-02-50,315-02-500
规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格:1418,9146,36654,582,16005,5494,23780
产品类型:细胞因子添加物
品牌:PeproTech
产品描述:M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells.Recombinant Murine M-CSF is a 36.4 kDa homodimeric protein consisting of two 156 amino acid polypeptide subunits.来源:E.coli别名:Macrophage Colony Stimulating Factor, CSF-1, MGI-IM氨基酸序列 (monomer):MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of the proliferation of M-NFS-60 cells is≤ 1.0 ng/ml, corresponding to a specific activity of≥ 1 x 106units/mg.Calculated Molecular Weight:36.4 kDaAccession Number:P07141Gene ID:12977交叉反应:Cow + Mouse,Human,Mouse,Rat原产地:USA仅用于科研,不能用于临床和诊断。 |
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