Recombinant Human/Murine/Rat BDNF
货号：450-02-10,450-02-100,450-02-1000,450-02-2,450-02-250,450-02-50,450-02-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,11069,44326,582,19355,6634,28757
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.别名:Brain Derived Neurotrophic Factor, Abrineurin氨基酸序列:MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to stimulate the proliferation of rat C6 cells. The expectedED50for this effect is 0.5-1.0 μg/ml.Calculated Molecular Weight:27 kDaAccession Number:P23560Gene ID:627交叉反应:Chicken,Frog,Guinea Pig,Hamster,Human,Human + Mouse,Human + Rat,Human + Virus,Monkey,Mouse,Rat,Tadpole,tests原产地:USA仅用于科研，不能用于临床和诊断。 |
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