Recombinant Murine Leptin
货号：450-31-1000,450-31-200,450-31-5mg
规格：1mg,200ug,5mg
价格：2570,1050,7700
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in variousin vivomodels. Recombinant Murine Leptin is a 16.2 kDa protein containing 147 amino acid residues.来源:E.coli别名:Obesity protein (OB)氨基酸序列:MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:PeproTech's Murine Leptin has been shown to be biologically active in two different mouse obesity models,ob/oband NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.Calculated Molecular Weight:16.2 kDaAccession Number:P41160Gene ID:16846交叉反应:Hamster,Human,Monkey,Mouse,Pig,Rat原产国:USA |
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